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Co-trimoxazole is a type of antibacterial medicine, which works by killing bacteria. Co-trimoxazole tablets are used to treat or prevent lung infections caused by Pneumocystis jiroveci (P.carinii ) or prevent toxoplasmosis (passed through undercooked meat or cat faeces) /nocardiosis (bacterial infection causing abscesses)/ urinary tract infections (e.g. cystitis) or worsening of long-term bronchitis/ear infections ( acute otitis media).
Do not take Co-trimoxazole tablets and tell your doctor if you:
1. are allergic (hypersensitive) to trimethoprim, sulphonamides or any of the other ingredients;
2. have sever liver damage or jaundice;
3. have any blood disorder or porphyria (a genetic disease);
4. have severe kidney disease;
5. are pregnant or planning to become pregnant;
6. Co-trimoxazole should not be given to newborn babies under 6 weeks old except for Pneumocystis jiroveci (P.carinii) infection.
Stop taking the tablets and contact a doctor at once if you get a skin rash, or severe allergic reaction such as swelling of the face, lips, tongue or throat, difficulty breathing, fever, inflamed heart or blood vessels (chest pain, fever, a fast heartbeat, tiredness), systemic lupus erythematosus (SLE-skin rash, hair loss, difficulty breathing and joint pains), Stevens-Johnson syndrome (severe skin rash with flushing, fever, blisters or ulcers) or toxic epidermal necrolysis (severe rash involving reddening, peeling and swelling of the skin that resembles severe burns).
Aseptic meningitis can occur in some patients as a combination of symptoms such as headache, fever, stiff neck, tiredness, feeling ill and sensitivity of eyes to bright light.
Co-trimoxazole should not be used in pregnancy. If you are breast-feeding, ask your doctor for advice before taking this medicine.